Recruitment

Speculative CVs are welcome, please send to: hr@missiontherapeutics.com

Scientist - in vivo pharmacology (permanent)  Reference M0025

We currently have an opening for an experienced in vivo scientist to join our pharmacology team.  The successful candidate will be involved in the day-to-day running and delivery of key preclinical in vivo assays and associated activities to aid selection and progression of MISSION’s candidate drugs from lead identification through to clinical nomination.  Specifically, you will provide hands-on in vivo pharmacology expertise for the discovery and development phases of the company’s small molecule drug discovery programmes.  This will include delivering PK/PD/efficacy studies in conjunction with MISSION’s biology teams, as well as supporting translational research on our anti-tumour programmes, and developing innovative preclinical models.  You will also be responsible for writing laboratory protocols and authoring study reports to support drug selection and regulatory filings.  The role will require some weekend work.

Essential skills & experience

  • Life science B.Sc. or equivalent experience
  • Home Office personal licensee with a thorough understanding of regulatory requirements
  • Working knowledge of preclinical ADME/PK/safety/efficacy models
  • Demonstrated expertise in applying in vivo oncology models to drug discovery cascade
  • Strong computer/software skills for data entry/analysis
  • Methodical with excellent attention to detail
  • Team player with good communication skills
  • Ability to work independently under minimal supervision

 

Desirable skills & experience

  • Experience working in a relevant industry/biotech environment
  • Model development/trouble-shooting skills
  • Skilled in general cell culture/molecular biology techniques
  • Surgical skills/understanding of aseptic techniques and good practice
  • Formulation experience
  • Demonstrable experience in colony management
  • Experience using statistical packages and data analysis
  • Appreciation of preclinical pharmacology assays as applied to drug discovery cascades
  • Ability to work to timelines and under pressure in a dynamic environment
  • Good problem solving skills

Benefits

We are located in new, purpose-built laboratories on the Babraham Research Campus.  We offer a competitive salary, along with a contributory pension scheme plus other benefits.

If you would like to apply for this position, please send your CV with a covering letter to hr@missiontherapeutics.com quoting reference number M0025 by 25th April, 2014.

 

Screening scientist (permanent) Reference M0026

We currently have an opening for an enthusiastic and experienced screening scientist to join on a permanent basis. The applicant will have previous laboratory experience and be educated to BSc, MSc or equivalent in a life science subject.  Ideally you will have hands-on experience with a broad range of scientific techniques along with an understanding of oncology.  The successful candidate will be involved in the day to day running of in vitro and cell based screening assays to support the company’s small molecule drug discovery process.  This will include plate based screening assays, protein production and assay development as well as use of databases to capture and analyse data.  Laboratory work is a major component of this role and a level of independence in experimental design and data analysis is required.

Essential skills

  • Life science B.Sc. or equivalent experience
  • Previous laboratory experience
  • Methodical with excellent attention to detail
  • Team player with good communication skills
  • Ability to work independently under minimal supervision

 

Desirable skills

  • Experience in running in vitro screening assays
  • Knowledge of screening technologies e.g.  FI, FP, HTRF
  • Proficient in tissue culture techniques
  • Knowledge of recombinant protein production and purification
  • Practical experience of assay development and troubleshooting
  • Strong computer/software skills for data entry/analysis

Benefits

We are located in new labs on the campus; we offer a competitive salary, along with a contributory pension scheme plus other excellent benefits.

If you wish to apply for this position, please send your CV with a covering letter to hr@missiontherapeutics.com quoting reference number M0026 by 9th May 2014

No agencies, thank you